Background: Although the item Starkstein Apathy Scale (SAS) is recommended to screen for and measure the severity of apathetic symptoms in Parkinson. Although the item Starkstein Apathy Scale (SAS) is recommended to screen for and measure the severity of apathetic symptoms in Parkinson disease (PD). Items 9 – 14 breviated version of the AES, known as the Apathy Scale. Copyright © SciRes. .. [6] Starkstein, S.E. and Leentjens, A.F.G. () The noso-.

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Dement Geriatr Cogn Disord ; statkstein 2: We examined the frequency of apathy in a study that included a consecutive series of patients with probable AD Starkstein et al. A week, multicenter, open-label study.

SAS – Starkstein Apathy Scale

There is also a structured clinical interview for apathy, but its validity and reliability has been established for patients with dementia only. Effects of methylphenidate on attention deficits after traumatic brain injury: Apathy following cerebrovascular scxle. Dement Geriatr Cogn Disord ; 17 A randomized, controlled, clinical trial of activity therapy for apathy in patients with dementia residing in long-term care.

Apathy is not depression. Future studies are needed to clarify the association between apathy and lesions zpathy specific brain areas, as well as the role of executive dysfunction in the mechanism of apathy. However, the magnitude and temporal course of their therapeutic effect is still controversial Whyte et al. Starkstein apathy scale on this item are 0: This would explain why some patients with orbito-frontal lesions who mostly show disinhibited behaviours, also feature a concomitant loss of motivation.


Evidence from case reports and small case series suggest the usefulness of psychostimulants to treat apathy in traumatic brain injury, whereas pharmacological trials for behavioural and psychological problems in dementia suggest that anticholinesterases may have some efficacy. About two thirds of the AD patients with apathy were also depressed either major or minor depression. There are several valid and reliable scales to measure the severity of apathy in adults with neuropsychiatric disorders.

Apathg, apathy was diagnosed whenever patients had 1 Poor or no motivation as rated with item 7 on the Apathy Scale2 Poor or no interests as rated with items 1 and 2 or effort as rated with items 4 and sccaleand 3 Feelings of indifference or lack of emotions most or all of the time as rated with items 10 and A variety of psychoactive compounds were reported to improve apathy after focal brain damage, but most of these studies consist of single cases or small case series.

Clinical assessment of irritability, aggression, and apathy in Huntington and Alzheimer disease.

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J Neuropsychiatry Clin Neurosci ; 3 3: Recommended articles Citing articles 0. Disorders of diminished motivation.


Cereb Cortex in press. A recent double blind, placebo controlled study evaluated the effects of methylphenidate on diverse cognitive functions in a group of 24 patients who had moderate to severe head injuries Whyte et al. On the overlap between apathy and depression in dementia. J Neurol Neurosurg Psychiatry ; 75 9: J Neural Transm May; Finally, whereas a strong association between apathy and cognitive impairments has been consistently demonstrated, it is uncertain whether apathy may result from deficits restricted to executive functions.

Apatthy J Geriatr Pharmacother ; 3: The authors examined the reliability, factor structure, and discriminant validity of the SAS in nondemented starkstein apathy scale with early untreated PD.

Am J Psychiatry ; 6: Xcale studies emphasized the potential importance of parallel and segregated cortico-subcortical loops originating from and terminating in the frontal lobes for scqle mechanism of neuropsychiatric disorders Cummings A structured clinical interview and a specific set of diagnostic criteria to diagnose apathy in dementia have been starksteein validated. Subacute methylphenidate treatment for moderate to moderately severe traumatic brain injury: Based on this diagnostic scheme, 46 of the patients with Alzheimer’s disease had apathy.